SV2B

Synaptic vesicle glycoprotein 2B
Identifiers
Symbols	SV2B ; HsT19680
External IDs	OMIM: 185861 MGI: 1927338 HomoloGene: 32236 ChEMBL: 1999 GeneCards: SV2B Gene
Gene ontology Molecular function • protein binding • transmembrane transporter activity Cellular component • acrosomal vesicle • plasma membrane • synaptic vesicle • membrane • integral component of membrane • cell junction • synaptic vesicle membrane Biological process • neurotransmitter transport • transmembrane transport Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9899	64176
Ensembl	ENSG00000185518	ENSMUSG00000053025
UniProt	Q7L1I2	Q8BG39
RefSeq (mRNA)	NM_001167580	NM_001109753
RefSeq (protein)	NP_001161052	NP_001103223
Location (UCSC)	Chr 15: 91.1 – 91.3 Mb	Chr 7: 75.11 – 75.31 Mb
PubMed search

Synaptic vesicle glycoprotein 2B is a protein that in humans is encoded by the SV2B gene.^[1][2][3]

See also

• SV2A

References

1. Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Apr 1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
2. Bajjalieh SM, Peterson K, Linial M, Scheller RH (Apr 1993). "Brain contains two forms of synaptic vesicle protein 2". Proc Natl Acad Sci U S A 90 (6): 2150–4. doi:10.1073/pnas.90.6.2150. PMC 46043. PMID 7681585.
3. "Entrez Gene: SV2B synaptic vesicle glycoprotein 2B".

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Lazzell DR, Belizaire R, Thakur P, et al. (2005). "SV2B regulates synaptotagmin 1 by direct interaction.". J. Biol. Chem. 279 (50): 52124–31. doi:10.1074/jbc.M407502200. PMID 15466855.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Janz R, Goda Y, Geppert M, et al. (2000). "SV2A and SV2B function as redundant Ca2+ regulators in neurotransmitter release.". Neuron 24 (4): 1003–16. doi:10.1016/S0896-6273(00)81046-6. PMID 10624962.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.