Saccharopepsin

Identifiers

Databases

IntEnz

IntEnz view

PDB structures

Search
PMC	articles
PubMed	articles
NCBI	proteins

Saccharopepsin (EC 3.4.23.25, yeast endopeptidase A, Saccharomyces aspartic proteinase, aspartic proteinase yscA, proteinase A, proteinase yscA, yeast proteinase A, Saccharomyces cerevisiae aspartic proteinase A, PRA) is an enzyme.^[1]^[2]^[3] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with broad specificity for peptide bonds. Cleaves -Leu-Leu-Val-Tyr bond in a synthetic substrate.

This enzyme is present in baker's yeast (Saccharomyces cerevisiae).

References

↑ Hata, T., Hayashi, R. and Dot, E. (1967). "Purification of yeast proteinases. Part III. Isolation and physicochemical properties of yeast proteinase A and C". Agric. Biol. Chem. 31: 357–367. doi:10.1080/00021369.1967.10858812.
↑ Meussdoerffer, F., Tortora, P. and Holzer, H. (1980). "Purification and properties of proteinase A from yeast". J. Biol. Chem. 255: 12087–12093. PMID 7002931.
↑ Ammerer, G., Hunter, C.P., Rothman, J.H., Saari, G.C., Valls, L.A. and Stevens, T.H. (1987). "PEP4 gene of Saccharomyces cerevisiae encodes proteinase A, a vacuolar enzyme required for processing of vacuolar precursors". Mol. Cell. Biol. 6: 2490–2499. PMID 3023936.

External links

Saccharopepsin at the US National Library of Medicine Medical Subject Headings (MeSH)

Proteases: aspartate proteases (EC 3.4.23)

Vertebrate	Pepsin Chymosin Renin Signal peptide peptidase Beta secretase 1 2

Pathogenic	Plasmepsin HIV-1 protease

Plant	Nepenthesin

Cathepsin	D E

Proteins: enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

This article is issued from Wikipedia - version of the Monday, January 25, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.