Samp1

Samp1, is an inner nuclear membrane protein in mammals. Samp1 is known to interact with SUN2 and lamin A/C, and is believed to be involved in the stabilizing of the LINC complex during cell mitosis, facilitating the anchoring to the lamina. Lamin A/C is required for samp1 presence at the inner nuclear membrane. Samp1 is homologous to the S. Pombe inner nuclear membrane protein Ima1.[1]

References

  1. ↑ Joana Borrego-Pinto et al.(2012) "Samp1 is a component of TAN lines and is required for nuclear movement"Journal of Cell Science 125, 1-7 doi= 10.1242/jcs.087049
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