Sattler's layer

Sattler's layer
Details
Latin	lamina vasculosa
Dorlands /Elsevier	l_05/12481039
Anatomical terminology [edit on Wikidata]

Sattler's layer is one of five (or six^{[lower-alpha 1]}) layers of medium-diameter blood vessels of the choroid, and a layer of the eye. It is situated between the Bruch's membrane, choriocapillaris and Haller's layer below, and the suprachoroidea above, respectively.^[1]

Several papers have shown the relationship between the thickness of the choroidal, Sattler's and Haller's layer in healthy individuals and in people with age-related macular degeneration (AMA).^[2][3] The studies showed significant reduction of layer thickness in relation to the progression of AMD, which may be important in the understanding of choroidopathy in the pathophysiology of AMD.^[3]

Notes

1. Some authors consider the vascular region of the choroid as being two separate layers, namely the Sattler's and Haller's layers, and some consider the lamina fusca as being either of scleral or choroidal origin.

References

1. L. Nickla, Debora; Wallman, Josh (2010). "The Multifunctional Choroid". Progress in Retinal and Eye Research 29 (2): 144–168. doi:10.1016/j.preteyeres.2009.12.002. PMC 2913695. PMID 20044062. Retrieved 15 February 2015.
2. Esmaeelpour, Marieh; Ansari-Shahrezaei, Siamak; Kellner, Lukas; Krebs, Ilse; Binder, Susanne (9 June 2014). "Choroidal Haller's and Sattler's Layer Thickness Measurement Using 3-Dimensional 1060-nm Optical Coherence Tomography". PLOS ONE 9 (6): e99690. doi:10.1371/journal.pone.0099690. Retrieved 15 February 2015.
3. Esmaeelpour, M.; Ansari-Shahrezaei, S.; Glittenberg, C.; Nemetz, S.; Kraus, M.F. (22 July 2014). "Choroid, Haller's, and Sattler's layer thickness in intermediate age-related macular degeneration with and without fellow neovascular eyes.". Investigative Ophthalmology & Visual Science 55 (8): 5074. doi:10.1167/iovs.14-14646. PMC 4132555. PMID 25052997. Retrieved 2015-02-15.