Scytalidopepsin A

Scytalidopepsin A
Identifiers
EC number	3.4.23.31
CAS number	42613-34-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Scytalidopepsin A (EC 3.4.23.31, Scytalidium aspartic proteinase A, Scytalidium lignicolum aspartic proteinase, Scytalidium lignicolum aspartic proteinase A-2, Scytalidium lignicolum aspartic proteinase A-I, Scytalidium lignicolum aspartic proteinase C, Scytalidium lignicolum carboxyl proteinase, Scytalidium lignicolum acid proteinase) is an enzyme.^[1][2][3] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with specificity similar to that of pepsin A, but also cleaves Cys(SO₃H)⁷-Gly and Leu¹⁷-Val in the B chain of insulin

This enzyme is isolated from the fungus Scytalidium lignicolum.

References

1. Oda, K. and Murao, S. (1974). "Purification and some enzymatic properties of acid protease A and B of Scytalidium lignicolum ATCC 24568". Agric. Biol. Chem. 38: 2435–2444. doi:10.1271/bbb1961.38.2435.
2. Oda, K. and Murao, S. (1976). "Action of Scytalidium lignicolum acid proteases on insulin B-chain". Agric. Biol. Chem. 40: 1221–1225. doi:10.1271/bbb1961.40.1221.
3. Oda, K., Torishima, H. and Murao, S. (1986). "Purification and characterization of acid proteinase C of Scytalidium lignicolum ATCC 24568". Agric. Biol. Chem. 50: 651–658. doi:10.1271/bbb1961.50.651.

External links

• Scytalidopepsin A at the US National Library of Medicine Medical Subject Headings (MeSH)