Selone

General chemical structure of a selone

In chemistry, a selone is the structural analog of a ketone where selenium replaces oxygen. Selones are used as chiral derivatizing agents for selenium-77 NMR spectroscopy.[1] Chiral oxazolidineselones are excellent partners in the stereospecific aldol reaction, and 77Se NMR can verify the enantiomeric purity of the aldol product.[2]

References

  1. ↑ J. Peng, J. D. Odom, R. B. Dunlap, and L. A. Silks III (1994). "Use of a selone chiral derivatizing agent for the absolute configurational assignment of stereogenic center". Tetrahedron: Asymmetry 5 (9): 1627–1630. doi:10.1016/0957-4166(94)80066-9.
  2. ↑ L. Silks, D. Kimball, D. Hatch; et al. (2009). "Chiral N-Acetyl Selone-Promoted Aldol Reactions". Synthetic Communications 39 (4): 641–653. doi:10.1080/00397910802419706.


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