Small Cajal body specific RNA 25

Small Cajal body specific RNA 3
Type: Gene; snRNA; snoRNA; scaRNA;
2° structure: Predicted; RNAalifold
Seed alignment: Marantidis E, INFERNAL
Avg length: 128.70 nucleotides
Avg identity: 74.00%

Small Cajal body specific RNA 25 (otherwise known as scaRNA25, HBI-100, MBI-100 and MBI-114) is a scaRNA, which are a class of ncRNAs characterised as small nuclear RNAs localised to the Cajal bodies.[1]

ScaRNA25 was originally identified in a large scale cloning project in mice.[2] Later sequence analysis predicted that this RNA guides the pseudouridylation of position U40 in the U6 snRNA.[2]

References

  1. ↑ Darzacq, Xavier; Jády, Beáta E.; Verheggen, Céline; Kiss, Arnold M.; Bertrand, Edouard; Kiss, Tamás (2002). "Cajal body-specific small nuclear RNAs: A novel class of 2'-O-methylation and pseudouridylation guide RNAs". The EMBO Journal 21 (11): 2746–2756. doi:10.1093/emboj/21.11.2746. PMC 126017. PMID 12032087.
  2. 1 2 Huttenhofer, Alexander; Kiefmann, Martin; Meier-Ewert, Sebastian; O'Brien, John; Lehrach, Hans; Bachellerie, Jean-Pierre; Brosius, Jürgen (1 June 2001). "RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse". The EMBO Journal 20 (11): 2943–2953. doi:10.1093/emboj/20.11.2943. PMC 125495. PMID 11387227.

External links


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