Snake venom factor V activator
Snake venom factor V activator (EC 3.4.21.95) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction
- Fully activates human clotting factor V by a single cleavage at the Trp-Tyr-Leu-Arg1545-Ser-Asn-Asn-Gly bond.
This enzyme is present in venom of Vipera russelli.
References
- ↑ Kisiel, W. and Canfield, W. (1981). "M. Snake venom proteases that activate blood-coagulation factor V". Methods Enzymol. 80: 275–285. doi:10.1016/s0076-6879(81)80024-9. PMID 7043192.
- ↑ Tokunaga, F., Nagasawa, K., Tamura, S., Miyata, T., Iwanaga, S. and Kisiel, W. (1988). "The factor V-activating enzyme (RVV-V) from Russell's viper venom. Identification of isoproteins RVV-Vα, -Vβ and -Vγ and their complete amino acid sequences". J. Biol. Chem. 263: 17417–17481. PMID 3053712.
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