Somatostatin family

Somatostatin/Cortistatin family
Identifiers
Symbol Somatostatin
Pfam PF03002
InterPro IPR004250

The Somatostatin family is a protein family with somatostatin as titular member, a hormone which inhibits the release of the pituitary somatotropin (growth hormone), and inhibits the release of glucagon and insulin from the pancreas of fasted animals. Cortistatin is a cortical neuropeptide with neuronal depressant and sleep-modulating properties.[1]

Human proteins from this family

CORT; SST;

References

  1. De Lecea L, Danielson PE, Criado JR, Prospero-garcia O, Gautvik KM, Schweitzer P, Dunlop CL, Siggins GR, Henriksen SJ, Sutcliffe JG (1996). "A cortical neuropeptide with neuronal depressant and sleep-modulating properties". Nature 381 (6579): 242–245. doi:10.1038/381242a0. PMID 8622767.

This article incorporates text from the public domain Pfam and InterPro IPR004250

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