Spike (database)

SPIKE

Content
Description	highly curated human signaling pathways.
Organisms	Homo sapiens
Contact
Research center	Sackler School of Medicine, Tel Aviv University, Israel.
Laboratory	Department of Human Molecular Genetics and Biochemistry,
Authors	Arnon Paz
Primary citation	Paz & al. (2011)[1]
Release date	2010
Access
Website	http://www.cs.tau.ac.il/~spike/
Download URL	http://www.cs.tau.ac.il/~spike/formats.html

SPIKE (Signaling Pathways Integrated Knowledge Engine) is a database of highly curated interactions for particular human pathways.^[1] SPIKE was developed by Ron Shamir's computational biology group in cooperation with the group of Yosef Shiloh, an Israel Prize recipient for his research in systems biology, and the group of Karen B. Avraham, a leading researcher of human deafness, all from Tel-Aviv University.

See also

• signaling pathways.

References

1. Paz, Arnon; Brownstein Zippora, Ber Yaara, Bialik Shani, David Eyal, Sagir Dorit, Ulitsky Igor, Elkon Ran, Kimchi Adi, Avraham Karen B, Shiloh Yosef, Shamir Ron (Jan 2011). "SPIKE: a database of highly curated human signaling pathways". Nucleic Acids Res. (England) 39 (Database issue): D793–9. doi:10.1093/nar/gkq1167. PMC 3014840. PMID 21097778. Cite uses deprecated parameter |coauthors= (help)

External links

• http://www.cs.tau.ac.il/~spike/