SpoIVB peptidase

SpoIVB peptidase
Identifiers
EC number 3.4.21.116
CAS number 296241-18-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

SpoIVB peptidase (EC 3.4.21.116, sporulation factor IV B protease) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction

Self-cleaves Val52-Asn53, Ala62-Phe63 and Val74-Thr75 at the N-terminus of SpoIVB

This enzyme participates in gene expression during the later stages of spore formation in Bacillus subtilis.

References

  1. Wakeley, P.R., Dorazi, R., Hoa, N.T., Bowyer, J.R. and Cutting, S.M. (2000). "Proteolysis of SpolVB is a critical determinant in signalling of pro-σK processing in Bacillus subtilis". Mol. Microbiol. 36: 1336–1348. doi:10.1046/j.1365-2958.2000.01946.x. PMID 10931284.
  2. Hoa, N.T., Brannigan, J.A. and Cutting, S.M. (2001). "The PDZ domain of the SpoIVB serine peptidase facilitates multiple functions". J. Bacteriol. 183: 4364–4373. doi:10.1128/jb.183.14.4364-4373.2001. PMID 11418578.
  3. Hoa, N.T., Brannigan, J.A. and Cutting, S.M. (2002). "The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases". J. Bacteriol. 184: 191–199. doi:10.1128/jb.184.1.191-199.2002. PMID 11741860.
  4. Dong, T.C. and Cutting, S.M. (2003). "SpoIVB-mediated cleavage of SpoIVFA could provide the intercellular signal to activate processing of pro-σK in Bacillus subtilis". Mol. Microbiol. 49: 1425–1434. doi:10.1046/j.1365-2958.2003.03651.x. PMID 12940997.

External links

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