List of highways numbered 105

Route 105 or Highway 105 may refer to:

Canada

• New Brunswick Route 105
• Nova Scotia Highway 105
• Ontario Highway 105
• Prince Edward Island Route 105
• Quebec Route 105

China

• China National Highway 105
• S105 Nansha Port Expressway (Guangdong)

India

• National Highway 105 (India)

Japan

• Route 105 (Japan)

United States

• Interstate 105
• Alabama State Route 105
• Colorado State Highway 105
• Florida State Road 105
• Georgia State Route 105
• Illinois Route 105
• Indiana State Road 105
• County Road 105 (Iowa)
• K-105 (Kansas highway)
• Louisiana Highway 105
• Maine State Route 105
• Massachusetts Route 105
• M-105 (Michigan highway) (former)
• Minnesota State Highway 105
• Missouri Route 105
• Nebraska Highway 105
• New Mexico State Road 105
• New York State Route 105
• North Carolina Highway 105
• Ohio State Route 105
• Oklahoma State Highway 105
• Pennsylvania Route 105 (former)
• South Carolina Highway 105
• South Dakota Highway 105 (former)
• Tennessee State Route 105
• Texas State Highway 105
• Utah State Route 105
• Vermont Route 105
  • Vermont Route 105A
• Virginia State Route 105
• Washington State Route 105
• West Virginia Route 105
• Wisconsin Highway 105