Stromal vascular fraction

Stromal vascular fraction

Stromal Vascular Fraction

Stromal vascular fraction (SVF) of adipose tissue is a rich source of preadipocytes, mesenchymal stem cells (MSC), endothelial progenitor cell, T cells, B cells, mast cells as well as adipose tissue macrophages.[1][2]

Introduction

Stromal Vascular Fraction (SVF) is a component of the lipoaspirate obtained from liposuction of excess adipose tissue. Lipoaspirate, the waste product of liposuction (cosmetic surgery), contains a large population of stem cells called adipose derived stem cells (ADSCs), which share a number of similarities with bone marrow stem cells, including the capacity for multilineage differentiation.

References

  1. ↑ Riordan, NH; Ichim, TE; Min, WP; Wang, H; Solano, F; Lara, F; Alfaro, M; Rodriguez, JP; Harman, RJ; Patel, AN; Murphy, MP; Lee, RR; Minev, B (Apr 24, 2009). "Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis.". Journal of translational medicine 7: 29. doi:10.1186/1479-5876-7-29. PMC 2679713. PMID 19393041.
  2. ↑ Schipper HS, Prakken B, Kalkhoven E, Boes M. Adipose tissue-resident immune cells: key players in immunometabolism. Trends Endocrinol Metab 2012; 23:407-15.
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