Substrate analog
For other uses, see Analog (disambiguation).
Substrate analogs (substrate state analogues), are chemical compounds with a chemical structure that resemble the substrate molecule in an enzyme-catalyzed chemical reaction. Substrate analogs can act as competitive inhibitors of an enzymatic reaction. An example is phosphoramidate to the Tetrahymena group I ribozyme[1]
See also
- Enzyme
- Enzyme inhibitor
- Suicide inhibitor
- Structural analog, compounds with similar chemical structure
References
- ↑ Hanna, Raven L.; Gryaznov, Sergei M.; Doudna, Jennifer A. (2000-11-01). "A phosphoramidate substrate analog is a competitive inhibitor of the Tetrahymena group I ribozyme". Chemistry & Biology 7 (11): 845–854. doi:10.1016/S1074-5521(00)00033-8. ISSN 1074-5521. PMID 11094338.
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