Sulfacytine

Sulfacytine

Systematic (IUPAC) name
4-amino-N-(1-ethyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzene-1-sulfonamide
Clinical data
Routes of administration	Oral
Identifiers
CAS Number	17784-12-2
PubChem	CID 5322
DrugBank	DB01298
ChemSpider	5131
UNII	T795873AJP
ChEMBL	CHEMBL1201056
Synonyms	1-ethyl N4-sulfanilylcytosin, 1-ethyl-N-sulfanilylcytosine, N-sulfanilyl-l-ethylcytosine, Sulfacitina [inn-spanish], Sulfacitinum [inn-latin]
Chemical data
Formula	C12H14N4O3S
Molar mass	294.33 g·mol^−1
SMILES CCN1C=CC(NS(=O)(=O)C2=CC=C(N)C=C2)=NC1=O
InChI InChI=InChI=1S/C12H14N4O3S/c1-2-16-8-7-11(14-12(16)17)15-20(18,19)10-5-3-9(13)4-6-10/h3-8H,2,13H2,1H3,(H,14,15,17) Key:SIBQAECNSSQUOD-UHFFFAOYSA-N

Sulfacytine is a short-acting sulfonamide antibiotic, taken orally for treatment against bacterial infections. Sulfonamides, as a group of antibiotics, work by inhibiting the bacterial synthesis of folate.^[1] In 2006 the drug was discontinued^[2][3]

References

1. DrugBank DB01298
2. Federal Register Section: Food and Drug Administration [Docket No. 2006N–0222] Merck & Co., Inc., et al.; Withdrawal of Approval of 65 New Drug Applications and 52 Abbreviated New Drug Applications] Vol. 71, No. 116 / Friday, June 16, 2006. p34941
3. FDA Orange book. Sulfacytine Page accessed May 12, 2015