TAPS (buffer)

TAPS (buffer)

Names
IUPAC name 3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propane-1-sulfonic acid
Other names N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic acid
Identifiers
CAS Number	29915-38-6
ChemSpider	108495
Jmol interactive 3D	Image
PubChem	121591
InChI InChI=1S/C7H17NO6S/c9-4-7(5-10,6-11)8-2-1-3-15(12,13)14/h8-11H,1-6H2,(H,12,13,14) Key: YNLCVAQJIKOXER-UHFFFAOYSA-N InChI=1/C7H17NO6S/c9-4-7(5-10,6-11)8-2-1-3-15(12,13)14/h8-11H,1-6H2,(H,12,13,14) Key: YNLCVAQJIKOXER-UHFFFAOYAP
SMILES C(CNC(CO)(CO)CO)CS(=O)(=O)O
Properties
Chemical formula	C7H17NO6S
Molar mass	243.28 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

TAPS is used to make buffer solutions. It has a pK_a value of 8.44 (ionic strength I=0, 25°C).^[1] It can be used to make buffer solutions in the pH range 7.7–9.1.

The pH (and pKa at I≠0) of the buffer solution changes with concentration and temperature, and this effect may be predicted using online calculators. ^[2] Binds Co(II), Ni(II). ^[3]

References

1. Goldberg, R.; Kishore, N.; Lennen, R. (2002). "Thermodynamic Quantities for the Ionization Reactions of Buffers" (PDF). J. Phys. Chem. Ref. Data 31: 231–370. doi:10.1063/1.1416902.
2. "Biological buffers". REACH Devices.
3. Machado, C. M. M.; Gameiro, P.; Soares, H. M. (2008). J. Solution Chem. 37 (5): 603–617. Missing or empty |title= (help)