TB10Cs2H2 snoRNA

Consensus structure of TB10Cs2H2

TB10Cs2H2 is a member of the H/ACA-like class of non-coding RNA (ncRNA) molecules that guide the sites of modification of uridines to pseudouridines of substrate RNAs. It is known as a small nucleolar RNA (snoRNA) thus named because of its cellular localization in the nucleolus of the eukaryotic cell. TB10Cs2H2 is predicted to guide the pseudouridylation of LSU5 ribosomal RNA (rRNA) at residue Ψ1173.[1]

References

  1. ↑ Liang, XH; Uliel, S; Hury, A; Barth, S; Doniger, T; Unger, R; Michaeli, S (May 2005). "A genome-wide analysis of C/D and H/ACA-like small nucleolar RNAs in Trypanosoma brucei reveals a trypanosome-specific pattern of rRNA modification.". RNA (New York, N.Y.) 11 (5): 619–45. doi:10.1261/rna.7174805. PMC 1370750. PMID 15840815. Retrieved 24 August 2011.
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