TCEA1

Transcription elongation factor A (SII), 1

PDB rendering based on 1tfi.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols TCEA1 ; GTF2S; SII; TCEA; TF2S; TFIIS
External IDs OMIM: 601425 MGI: 1196624 HomoloGene: 55984 GeneCards: TCEA1 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 6917 21399
Ensembl ENSG00000187735 ENSMUSG00000033813
UniProt P23193 P10711
RefSeq (mRNA) NM_006756 NM_001159750
RefSeq (protein) NP_006747 NP_001153222
Location (UCSC) Chr 8:
53.97 – 54.02 Mb
Chr 1:
4.86 – 4.9 Mb
PubMed search

Transcription elongation factor A protein 1 is a protein that in humans is encoded by the TCEA1 gene.[1][2][3]

Interactions

TCEA1 has been shown to interact with GTF2H1[4][5] and POLR2A.[6][4][5]

References

  1. DiMarco SP, Glover TW, Miller DE, Reines D, Warren ST (Feb 1997). "Transcription elongation factor SII (TCEA) maps to human chromosome 3p22 --> p21.3". Genomics 36 (1): 185–8. doi:10.1006/geno.1996.0443. PMID 8812434.
  2. Park H, Baek K, Jeon C, Agarwal K, Yoo O (Mar 1994). "Characterization of the gene encoding the human transcriptional elongation factor TFIIS". Gene 139 (2): 263–7. doi:10.1016/0378-1119(94)90767-6. PMID 8112616.
  3. "Entrez Gene: TCEA1 transcription elongation factor A (SII), 1".
  4. 1 2 Archambault, J; Pan G; Dahmus G K; Cartier M; Marshall N; Zhang S; Dahmus M E; Greenblatt J (Oct 1998). "FCP1, the RAP74-interacting subunit of a human protein phosphatase that dephosphorylates the carboxyl-terminal domain of RNA polymerase IIO". J. Biol. Chem. (UNITED STATES) 273 (42): 27593–601. doi:10.1074/jbc.273.42.27593. ISSN 0021-9258. PMID 9765293.
  5. 1 2 Pan, G; Aso T; Greenblatt J (Sep 1997). "Interaction of elongation factors TFIIS and elongin A with a human RNA polymerase II holoenzyme capable of promoter-specific initiation and responsive to transcriptional activators". J. Biol. Chem. (UNITED STATES) 272 (39): 24563–71. doi:10.1074/jbc.272.39.24563. ISSN 0021-9258. PMID 9305922.
  6. Kettenberger, Hubert; Armache Karim-Jean; Cramer Patrick (Aug 2003). "Architecture of the RNA polymerase II-TFIIS complex and implications for mRNA cleavage". Cell (United States) 114 (3): 347–57. doi:10.1016/S0092-8674(03)00598-1. ISSN 0092-8674. PMID 12914699.

Further reading

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