TINAG
| Tubulointerstitial nephritis antigen | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | TINAG ; TIN-AG | ||||||||||||
| External IDs | OMIM: 606749 MGI: 1349477 HomoloGene: 8082 GeneCards: TINAG Gene | ||||||||||||
| |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 27283 | 26944 | |||||||||||
| Ensembl | ENSG00000137251 | ENSMUSG00000032357 | |||||||||||
| UniProt | Q9UJW2 | n/a | |||||||||||
| RefSeq (mRNA) | NM_014464 | NM_012033 | |||||||||||
| RefSeq (protein) | NP_055279 | NP_036163 | |||||||||||
| Location (UCSC) |
Chr 6: 54.31 – 54.39 Mb |
Chr 9: 76.95 – 77.05 Mb | |||||||||||
| PubMed search | |||||||||||||
Tubulointerstitial nephritis antigen is a protein that in humans is encoded by the TINAG gene.[1][2]
TINAG is a basement membrane glycoprotein initially identified as a target of antibodies in some forms of immunologically mediated tubulointerstitial nephritis.[supplied by OMIM][2]
References
- ↑ Ikeda M, Takemura T, Hino S, Yoshioka K (Mar 2000). "Molecular cloning, expression, and chromosomal localization of a human tubulointerstitial nephritis antigen". Biochem Biophys Res Commun 268 (1): 225–30. doi:10.1006/bbrc.2000.2103. PMID 10652240.
- 1 2 "Entrez Gene: TINAG tubulointerstitial nephritis antigen".
Further reading
- Katz A, Fish AJ, Santamaria P, et al. (1993). "Role of antibodies to tubulointerstitial nephritis antigen in human anti-tubular basement membrane nephritis associated with membranous nephropathy". Am. J. Med. 93 (6): 691–8. doi:10.1016/0002-9343(92)90205-P. PMID 1466368.
- Butkowski RJ, Kleppel MM, Katz A, et al. (1992). "Distribution of tubulointerstitial nephritis antigen and evidence for multiple forms". Kidney Int. 40 (5): 838–46. doi:10.1038/ki.1991.283. PMID 1762287.
- Fliger FD, Wieslander J, Brentjens JR, et al. (1987). "Identification of a target antigen in human anti-tubular basement membrane nephritis". Kidney Int. 31 (3): 800–7. doi:10.1038/ki.1987.69. PMID 3553704.
- Chen Y, Krishnamurti U, Wayner EA, et al. (1996). "REceptors in proximal tubular epithelial cells for tubulointerstitial nephritis antigen". Kidney Int. 49 (1): 153–7. doi:10.1038/ki.1996.20. PMID 8770961.
- Nelson TR, Kim Y, Michael AF, et al. (1999). "Tubulointerstitial nephritis antigen (TIN-ag) is expressed in distinct segments of the developing human nephron". Connect. Tissue Res. 37 (1–2): 53–60. doi:10.3109/03008209809028899. PMID 9643646.
- Kim SH, Kaminker P, Campisi J (1999). "TIN2, a new regulator of telomere length in human cells". Nat. Genet. 23 (4): 405–12. doi:10.1038/70508. PMID 10581025.
- Zhou B, Nelson TR, Kashtan C, et al. (2000). "Identification of two alternatively spliced forms of human tubulointerstitial nephritis antigen (TIN-Ag)". J. Am. Soc. Nephrol. 11 (4): 658–68. PMID 10752525.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
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