TMEM219
| Transmembrane protein 219 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | TMEM219 ; IGFBP-3R | ||||||||||
| External IDs | HomoloGene: 19263 GeneCards: TMEM219 Gene | ||||||||||
| |||||||||||
| Orthologs | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | 124446 | 68742 | |||||||||
| Ensembl | ENSG00000149932 | ENSMUSG00000060538 | |||||||||
| UniProt | Q86XT9 | Q9D123 | |||||||||
| RefSeq (mRNA) | NM_001083613 | NM_026827 | |||||||||
| RefSeq (protein) | NP_001077082 | NP_081103 | |||||||||
| Location (UCSC) |
Chr 16: 29.94 – 29.97 Mb |
Chr 7: 126.89 – 126.92 Mb | |||||||||
| PubMed search | |||||||||||
Transmembrane protein 219 also known as insulin-like growth factor-binding protein 3 receptor or IGFBP-3R is a protein that in humans is encoded by the TMEM219 gene.[1] IGFBP-3R acts as a cell death receptor for IGFBP3.[2]
References
- ↑ "Entrez Gene: Transmembrane protein 219".
- ↑ Ingermann AR, Yang YF, Han J, Mikami A, Garza AE, Mohanraj L, Fan L, Idowu M, Ware JL, Kim HS, Lee DY, Oh Y (September 2010). "Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer". J. Biol. Chem. 285 (39): 30233–46. doi:10.1074/jbc.M110.122226. PMC 2943278. PMID 20353938.
This article is issued from Wikipedia - version of the Monday, December 15, 2014. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.