Temple F. Smith

Temple F. Smith

Temple F. Smith
Born March 7, 1939
Auburn, New York
Known for Smith-Waterman algorithm
Notable awards ISCB Accomplishment by a Senior Scientist Award[1]

Temple F. Smith is a university professor in biomedical engineering[2][3] who helped to develop the Smith-Waterman algorithm with Michael Waterman in 1981. The Smith-Waterman algorithm serves as the basis for multi sequence comparisons, identifying the segment with the maximum local sequence similarity, see sequence alignment. This algorithm is used for identifying similar DNA, RNA and protein segments. He was director of the BioMolecular Engineering Research Center at Boston University for twenty years and is now Professor Emeritus.

Education

He obtained his bachelor's degree in 1963 from the Physics Department, Purdue University, West Lafayette, Indiana, U.S., and thereafter he graduated with a PhD. in 1969 in the Physics Department, University of Colorado at Boulder. Consecutively, he did his Postdoctoral research (March 1969 - August 1971) in the Department of Biophysics and Genetics, University of Colorado Medical School, Boulder.

Interests

His research is centered on the application of various computer science and mathematical methods for the discovery of the syntactic and semantic patterns in nucleic acid and amino acid sequences. In recent years this has focus on molecular evolution of protein families. such as the WD-repeat beta propellers, translation associated GTPase, and the ribosomal proteins.[4]

Notable Appointments/Positions Held

Selected publications

References


This article is issued from Wikipedia - version of the Sunday, March 20, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.