Tetrahydroharman

Tetrahydroharman
Names
Preferred IUPAC name
1-Methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
Systematic IUPAC name
1-Methyl-1H,2H,3H,4H,9H-pyrido[3,4-b]indole
Other names
Elaeagnine
Methtryptoline
Tetrahydroharmane
Identifiers
525-40-6 N
23844-21-5 (1S) YesY
2254-36-6 (1R) YesY
2506-10-7 N
3DMet B02674
ChEBI CHEBI:311872 N
ChemSpider 82643 N
614612 (1S) YesY
390581 (1R) YesY
EC Number 219-711-4
Jmol interactive 3D Image
KEGG C09089 N
MeSH Tetrahydroharmane
PubChem 91522 ()
704991 (1S)
442025 (1R)
Properties
C12H14N2
Molar mass 186.25296 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Tetrahydroharman(e), also known as 1-methyl-1,2,3,4-tetrahydro-β-carboline, is a general name for one of two isomers:

  1. (1S)-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
  2. Calligonine ((1R)-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole)

Calligonine is a major alkaloid constituent of the roots of Calligonum minimum and the bark of Elaeagnus angustifolia. When taken internally, it has the effect of substantially lowering blood pressure for an extended period of time, similar to reserpine.

References

See also

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