Time-lapse embryo imaging

Time-lapse embryo imaging is an emerging non-invasive embryo selection technique used in reproductive biology. It is used to help select embryos with lower risk of defects and/or greater potential of implantation. The procedure involves taking thousands of pictures of the growing embryo in vitro during incubation to study morphology and morphokinetic parameters.[1]

There is currently insufficient evidence of a difference in pregnancy rates, live-birth, stillbirth or miscarriage to choose been time-lapse embryo imaging or conventional embryo assessment in in-vitro fertilisation (IVF).[2] Further trials are needed in order to determine whether time-lapse embryo imaging can impact on outcomes such as live-birth for couples undergoing IVF or ICSI.[3]

References

  1. ↑ Montag, M.; Toth, B.; Strowitzki, T. (2013). "New approaches to embryo selection". Reproductive BioMedicine Online 27: 539–546. doi:10.1016/j.rbmo.2013.05.013. PMID 23933036.
  2. ↑ Armstrong, S; Arroll, N; Cree, LM; Jordan, V; Farquhar, C (27 February 2015). "Time-lapse systems for embryo incubation and assessment in assisted reproduction.". The Cochrane database of systematic reviews 2: CD011320. doi:10.1002/14651858.CD011320.pub2. PMID 25721906.
  3. ↑ Armstrong, S; Vail, A; Mastenbroek, S; Jordan, V; Farquhar, C (January 2015). "Time-lapse in the IVF-lab: how should we assess potential benefit?". Human reproduction (Oxford, England) 30 (1): 3–8. doi:10.1093/humrep/deu250. PMID 25316446.


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