Tinyatoxin

Tinyatoxin
Identifiers
58821-95-7 YesY
MeSH tinyatoxin
PubChem 442098
Properties
C36H38O8
Molar mass 598.69 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
YesY verify (what is YesYN ?)
Infobox references
Tinyatoxin
Heat Above Peak (SR: 5,300,000,000)

Tinyatoxin (TTX or TTN) is a highly irritant analog of resiniferatoxin and capsaicin. It occurs naturally in Euphorbia poissonii.[1]

It is a neurotoxin and (like its analogs) acts via vanilloid receptors of sensory nerves.[2] Tinyatoxin has a potential for pharmaceutical uses similar to uses of capsaicin. Tinyatoxin is about one third as strong as resiniferatoxin.

References

  1. Euphorbia poissonii in BoDD Botanical Dermatology Database
  2. Szallasi, A. and Blumberg, P.M. (1991). "Characterization of vanilloid receptors in the dorsal horn of pig spinal cord". Brain Res 547 (2): 335–338. doi:10.1016/0006-8993(91)90982-2. PMID 1884211.
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