Tooth regeneration
Tooth regeneration is a stem cell based regenerative medicine procedure in the field of tissue engineering and stem cell biology to replace damaged or lost teeth by regrowing them from autologous stem cells.[1]
As a source of the new bioengineered teeth somatic stem cells are collected and reprogrammed to induced pluripotent stem cells which can be placed in the dental lamina directly or placed in a reabsorbable biopolymer[2] in the shape of the new tooth [3]
History
Young et al.[4] first demonstrated in 2002 that teeth could be regenerated from cells.[5]
See also
- Epithelial cell rests of Malassez
- Polyphyodont
- Regenerative endodontics
- Socket preservation
- Tooth development
References
- ↑ Keishi Otsu, Mika Kumakami-Sakano, Naoki Fujiwara, Kazuko Kikuchi, Laetitia Keller, Hervé Lesot, and Hidemitsu Harada (February 4, 2014). "Stem cell sources for tooth regeneration: current status and future prospects". Frontiers in Physiology 5: 36. doi:10.3389/fphys.2014.00036. PMC 3912331. PMID 24550845. Retrieved June 16, 2014.
- ↑ Biopolymer methods in tissue engineering
- ↑ Hill, David J. (2012-05-10). "Toothless no more – Researchers using stem cells to grow new teeth". Singularity Hub. Retrieved June 16, 2014.
- ↑ Young CS, Terada S, Vacanti JP, Honda M, Bartlett JD, Yelick PC (2002). "Tissue engineering of complex tooth structures on biodegradable polymer scaffolds.". J Dent Res 81 (10): 695–700. doi:10.1177/154405910208101008. PMID 12351668.
- ↑ Yoshikazu Mikami -2012-Advances in tooth regeneration techniques
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