Transcription termination factor, RNA polymerase I

Transcription termination factor, RNA polymerase I
Identifiers
Symbols	TTF1 ; TTF-1; TTF-I
External IDs	OMIM: 600777 MGI: 105044 HomoloGene: 135863 GeneCards: TTF1 Gene
Gene ontology Molecular function • DNA binding • chromatin binding Cellular component • nucleus • nucleoplasm • nucleolus • cytoplasm • plasma membrane Biological process • chromatin remodeling • DNA-templated transcription, termination • regulation of transcription, DNA-templated • transcription from RNA polymerase I promoter • transcription initiation from RNA polymerase I promoter • termination of RNA polymerase I transcription • negative regulation of DNA replication • gene expression • regulation of gene expression, epigenetic • negative regulation of gene expression, epigenetic Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	7270	22130
Ensembl	ENSG00000125482	ENSMUSG00000026803
UniProt	Q15361	Q62187
RefSeq (mRNA)	NM_001205296	NM_009442
RefSeq (protein)	NP_001192225	NP_033468
Location (UCSC)	Chr 9: 132.38 – 132.41 Mb	Chr 2: 29.06 – 29.09 Mb
PubMed search

Transcription termination factor 1 is a protein that in humans is encoded by the TTF1 gene.^[1][2]

References

1. Evers R, Grummt I (Aug 1995). "Molecular coevolution of mammalian ribosomal gene terminator sequences and the transcription termination factor TTF-I". Proc Natl Acad Sci U S A 92 (13): 5827–31. doi:10.1073/pnas.92.13.5827. PMC 41594. PMID 7597036.
2. "Entrez Gene: TTF1 transcription termination factor, RNA polymerase I".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Jansa P, Mason SW, Hoffmann-Rohrer U, Grummt I (1998). "Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes.". EMBO J. 17 (10): 2855–64. doi:10.1093/emboj/17.10.2855. PMC 1170626. PMID 9582279.
• Muth V, Nadaud S, Grummt I, Voit R (2001). "Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription.". EMBO J. 20 (6): 1353–62. doi:10.1093/emboj/20.6.1353. PMC 145524. PMID 11250901.
• Strohner R, Nemeth A, Jansa P, et al. (2001). "NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines.". EMBO J. 20 (17): 4892–900. doi:10.1093/emboj/20.17.4892. PMC 125270. PMID 11532953.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9.". Nature 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
• Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway.". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle.". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
• Takano T, Ito Y, Matsuzuka F, et al. (2007). "Quantitative measurement of telomerase reverse transcriptase, thyroglobulin and thyroid transcription factor 1 mRNAs in anaplastic thyroid carcinoma tissues and cell lines.". Oncol. Rep. 18 (3): 715–20. doi:10.3892/or.18.3.715. PMID 17671725.