Translation initiation factor IF-3
| Translation initiation factor IF-3, N-terminal domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 translation initiation factor 3 n-terminal domain | |||||||||
| Identifiers | |||||||||
| Symbol | IF3_N | ||||||||
| Pfam | PF05198 | ||||||||
| InterPro | IPR019814 | ||||||||
| PROSITE | PDOC00723 | ||||||||
| SCOP | 1tif | ||||||||
| SUPERFAMILY | 1tif | ||||||||
| |||||||||
| Translation initiation factor IF-3, C-terminal domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 translation initiation factor 3 c-terminal domain | |||||||||
| Identifiers | |||||||||
| Symbol | IF3_C | ||||||||
| Pfam | PF00707 | ||||||||
| InterPro | IPR019815 | ||||||||
| PROSITE | PDOC00723 | ||||||||
| SCOP | 1tif | ||||||||
| SUPERFAMILY | 1tif | ||||||||
| |||||||||
In molecular biology, translation initiation factor IF-3 (gene infC) is one of the three factors required for the initiation of protein biosynthesis in bacteria. IF-3 is thought to function as a fidelity factor during the assembly of the ternary initiation complex which consists of the 30S ribosomal subunit, the initiator tRNA and the messenger RNA. IF-3 is a basic protein that binds to the 30S ribosomal subunit.[1] The chloroplast initiation factor IF-3(chl) is a protein that enhances the poly(A,U,G)-dependent binding of the initiator tRNA to chloroplast ribosomal 30s subunits in which the central section is evolutionary related to the sequence of bacterial IF-3.[2]
References
- ↑ Liveris D, Schwartz JJ, Geertman R, Schwartz I (September 1993). "Molecular cloning and sequencing of infC, the gene encoding translation initiation factor IF3, from four enterobacterial species". FEMS Microbiol. Lett. 112 (2): 211–6. doi:10.1111/j.1574-6968.1993.tb06450.x. PMID 8405963.
- ↑ Lin Q, Ma L, Burkhart W, Spremulli LL (April 1994). "Isolation and characterization of cDNA clones for chloroplast translational initiation factor-3 from Euglena gracilis". J. Biol. Chem. 269 (13): 9436–44. PMID 8144528.
This article incorporates text from the public domain Pfam and InterPro IPR019815
This article incorporates text from the public domain Pfam and InterPro IPR019814