Translocated actin-recruiting phosphoprotein

Translocated actin-recruiting phosphoprotein
Identifiers
Symbol tarp
UniProt O84462

The translocated actin-recruiting phosphoprotein (Tarp) is a protein that may mediate the invasion of epithelial cells by Chlamydia trachomatis using a type three secretion system.[1][2][3][4][5]

References

  1. Wang J, Chen L, Chen F, Zhang X, Zhang Y, Baseman J, Perdue S, Yeh IT, Shain R, Holland M, Bailey R, Mabey D, Yu P, Zhong G (2009), "A chlamydial type III-secreted effector protein (Tarp) is predominantly recognized by antibodies from humans infected with Chlamydia trachomatis and induces protective immunity against upper genital tract pathologies in mice", Vaccine 27 (22): 2967–2980, doi:10.1016/j.vaccine.2009.02.095, PMC 2680781, PMID 19428908
  2. Clifton DR, Dooley CA, Grieshaber SS, Carabeo RA, Fields KA, Hackstadt T (2005), "Tyrosine phosphorylation of the Chlamydial effector protein Tarp is species specific and not required for recruitment of actin", Infection and Immunity 73 (7): 3860–3868, doi:10.1128/IAI.73.7.3860-3868.2005, PMC 1168552, PMID 15972471
  3. Clifton DR, Fields KA, Grieshaber SS, Dooley CA, Fischer ER, Mead DJ, Carabeo RA, Hackstadt T (2004), "A chlamydial type III translocated protein is tyrosine-phosphorylated at the site of entry and associated with recruitment of actin", Proceedings of the National Academy of Sciences of the USA 6 (101): 10166–10171, doi:10.1073/pnas.0402829101, PMC 454183, PMID 15199184
  4. Engel J (2004), "Tarp and Arp: How Chlamydia induces its own entry", Proceedings of the National Academy of Sciences of the USA 101 (27): 9947–9948, doi:10.1073/pnas.0403633101, PMC 454194, PMID 15226494
  5. http://www.ncbi.nlm.nih.gov/protein/AAT47185.1?ordinalpos=1&itool=EntrezSystem2.PEntrez.Sequence.Sequence_ResultsPanel.Sequence_RVDocSum


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