Triploid syndrome

Triploid syndrome
A karyotype of a person who has this genetic disorder.
Classification and external resources
Specialty	medical genetics
ICD-10	Q92.7
ICD-9-CM	758.5
DiseasesDB	32658
MeSH	D057885
Orphanet	3376

Triploid syndrome is an extremely rare chromosomal disorder. Individuals with triploid syndrome have three of every chromosome, i.e. a total of sixty-nine rather than the normal forty-six chromosomes.

Fetuses with triploid syndrome are usually lost through early miscarriage. However, some infants have been born and survived as long as 10.5 months. Affected infants are usually small and have multiple birth defects. Those who survive are usually mosaic, meaning that some cells have the normal number of 46 chromosomes and some cells have 69. There are some people with Mosaic Triploidy who are in their 30s. There have been only around 60 recorded cases in the world.

Also known as

• 69,XXX^[1]
• 2n/3n Mixoploidy
• 3n Syndrome
• Chromosome Triploidy Syndrome
• Diploid/Triploid Mixoploidy
• Triploidy
• Triploidy Syndrome

See also

• Polyploid

References

1. Erol O, Erol M, Karaca M (October 2013). "Complete chorioamniotic separation and persistence of a yolk sac associated with triploidy". Journal of Obstetrics and Gynaecology Canada 35 (10): 914–6. PMID 24165059.