Uncoupling (neuropsychopharmacology)

In neuropsychopharmacology, uncoupling, also known as decoupling, is the process of receptor- or ligand-binding sites or domains becoming separated, moving alignments and/or becoming internalised as a result of drug tolerance resulting from prolonged exposure to bioavailable psychoactive substances or toxins.

This article is issued from Wikipedia - version of the Tuesday, June 10, 2014. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.