Ure2

YNL229C, also known as Ure2 or Ure3,[1] which stands for Ureidosuccinate transport, is a yeast gene that is responsible for both repressing nitrogen catabolism of glutamate by controlling the GLN3 transcription factor and for responding to oxidative stress. It is an open reading frame, meaning that it does not contain a stop codon.[2]

This code has been fully sequenced in Saccharomyces cerevisiae. It encodes 354 amino acids and has a molecular weight of 40,226. It has been mapped to chromosome XIV, 5.9 map units from petX and 3.4 map units from kex2.[3]

References

  1. ↑ Wickner, R.B. (1994). "[URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae.". Science 264 (5158): 566–569. doi:10.1126/science.7909170. PMID 7909170.
  2. ↑ Magasanik, B. (2005). "The transduction of the nitrogen regulation signal in Saccharomyces cerevisiae". Proc. Natl. Acad. Sci. USA 102: 16537–16538. doi:10.1073/pnas.0507116102.
  3. ↑ Coschigano, P.W.; Magasanik, B. (February 1991). "The URE2 gene product of Saccharomyces cerevisiae plays an important role in the cellular response to the nitrogen source and has homology to glutathione s-transferases.". Molecular and Cellular Biology 11 (2).

External links

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