VEZT

Vezatin, adherens junctions transmembrane protein
Identifiers
Symbols	VEZT ; VEZATIN
External IDs	MGI: 2143698 HomoloGene: 9739 GeneCards: VEZT Gene
Gene ontology Molecular function • myosin binding Cellular component • acrosomal vesicle • stereocilia ankle link complex • nucleoplasm • cytoplasm • plasma membrane • adherens junction • integral component of membrane Biological process • single organismal cell-cell adhesion • chordate embryonic development Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55591	215008
Ensembl	ENSG00000028203	ENSMUSG00000036099
UniProt	Q9HBM0	Q3ZK22
RefSeq (mRNA)	NM_017599	NM_001304572
RefSeq (protein)	NP_060069	NP_001291501
Location (UCSC)	Chr 12: 95.22 – 95.3 Mb	Chr 10: 93.94 – 94.04 Mb
PubMed search

Vezatin is a protein that in humans is encoded by the VEZT gene.^[1][2][3] The protein is documented as an adherens junction component in a number of cell types.

Interactions

VEZT has been shown to interact with MYO7A.^[1]

References

1. Küssel-Andermann P, El-Amraoui A, Safieddine S, Nouaille S, Perfettini I, Lecuit M, Cossart P, Wolfrum U, Petit C (November 2000). "Vezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin-catenins complex". The EMBO Journal 19 (22): 6020–9. doi:10.1093/emboj/19.22.6020. PMC 305826. PMID 11080149.
2. Hyenne V, Louvet-Vallée S, El-Amraoui A, Petit C, Maro B, Simmler MC (November 2005). "Vezatin, a protein associated to adherens junctions, is required for mouse blastocyst morphogenesis". Developmental Biology 287 (1): 180–91. doi:10.1016/j.ydbio.2005.09.004. PMID 16199027.
3. "Entrez Gene: VEZT vezatin, adherens junctions transmembrane protein".

Further reading

• Blaschuk OW, Rowlands TM (2003). "Plasma membrane components of adherens junctions (Review)". Molecular Membrane Biology 19 (2): 75–80. doi:10.1080/09687680210132467. PMID 12126233.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.