Vitelline membrane

Vitelline membrane
Details
Identifiers
Latin membrana vitellina
MeSH A16.631.886
Dorlands
/Elsevier
m_08/12523303

Anatomical terminology

The vitelline membrane is a structure surrounding the outer surface of the plasma membrane of an ovum. It is composed mostly of protein fibers, with protein receptors needed for sperm binding which, in turn, are bound to sperm plasma membrane receptors. The species-specificity between these receptors contributes to prevention of breeding between different species.

It is called zona pellucida in mammals.

As soon as the spermatozoon fuses with the ovum, signal transduction occurs, resulting in an increase of cytoplasmic calcium ions. This itself triggers the cortical reaction, which results in depositing several substances onto the vitelline membrane through exocytosis of the cortical granules, transforming it into a hard layer called the “fertilization membrane”, which serves as a barrier inaccessible to other spermatozoa. This phenomenon is the slow block to polyspermy.

See also

References

This article incorporates text in the public domain from the 20th edition of Gray's Anatomy (1918)


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