WDHD1

WD repeat and HMG-box DNA binding protein 1
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 2D7L​
Identifiers
Symbols	WDHD1 ; AND-1; AND1; CHTF4; CTF4
External IDs	OMIM: 608126 HomoloGene: 56019 GeneCards: WDHD1 Gene
Gene ontology Molecular function • DNA binding • chromatin binding • RNA binding • protein binding • RNA polymerase binding Cellular component • chromosome, centromeric region • nucleoplasm • cytoplasm Biological process • RNA processing • regulation of chromosome organization • heterochromatin maintenance Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	11169	218973
Ensembl	ENSG00000198554	ENSMUSG00000037572
UniProt	O75717	P59328
RefSeq (mRNA)	NM_001008396	NM_172598
RefSeq (protein)	NP_001008397	NP_766186
Location (UCSC)	Chr 14: 54.94 – 55.03 Mb	Chr 14: 47.24 – 47.28 Mb
PubMed search

WD repeat and HMG-box DNA binding protein 1 is a protein in humans that is encoded by the WDHD1 gene. ^[1]

The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

References

1. "Entrez Gene: WD repeat and HMG-box DNA binding protein 1". Retrieved 2013-02-18.

Further reading