WDR46

WD repeat domain 46
Identifiers
Symbols	WDR46 ; BING4; C6orf11; FP221; UTP7
External IDs	OMIM: 611440 MGI: 1931871 HomoloGene: 3981 GeneCards: WDR46 Gene
Gene ontology Molecular function • poly(A) RNA binding Cellular component • cellular_component • nucleolus • 90S preribosome • small-subunit processome Biological process • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) • biological_process • positive regulation of protein targeting to mitochondrion Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9277	57315
Ensembl	ENSG00000204221	ENSMUSG00000024312
UniProt	O15213	Q9Z0H1
RefSeq (mRNA)	NM_001164267	NM_020603
RefSeq (protein)	NP_001157739	NP_065628
Location (UCSC)	Chr 6: 33.28 – 33.29 Mb	Chr 17: 33.94 – 33.95 Mb
PubMed search

WD repeat-containing protein 46 is a protein that in humans is encoded by the WDR46 gene.^[1][2][3]

References

1. Herberg JA, Beck S, Trowsdale J (May 1998). "TAPASIN, DAXX, RGL2, HKE2 and four new genes (BING 1, 3 to 5) form a dense cluster at the centromeric end of the MHC". J Mol Biol 277 (4): 839–57. doi:10.1006/jmbi.1998.1637. PMID 9545376.
2. Herberg JA, Sgouros J, Jones T, Copeman J, Humphray SJ, Sheer D, Cresswell P, Beck S, Trowsdale J (Mar 1998). "Genomic analysis of the Tapasin gene, located close to the TAP loci in the MHC". Eur J Immunol 28 (2): 459–67. doi:10.1002/(SICI)1521-4141(199802)28:02<459::AID-IMMU459>3.0.CO;2-Z. PMID 9521053.
3. "Entrez Gene: WDR46 WD repeat domain 46".

Further reading

• Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus.". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression.". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics.". Nature 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle.". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.