Yt antigen system

The Yt antigen system (also known as Cartwright) is present on the membrane of red blood cells and helps determine a person's blood type. The antigens are found on the protein acetylcholinesterase, an enzyme which helps break down acetylcholine.^[1] The Yt system features two alleles, Yt(a) and Yt(b). Antibodies against the Yt system can lead to transfusion reactions such as hemolytic anemia.

References

Online 'Mendelian Inheritance in Man' (OMIM) 112100 - OMIM page on Yt antigen

↑ Bartels, CF; Zelinski, T; Lockridge, O (1993). "Mutation at codon 322 in the human acetylcholinesterase (ACHE) gene accounts for YT blood group polymorphism". American Journal of Human Genetics 52 (5): 928–36. PMC 1682033. PMID 8488842.

External links

Yt at BGMUT Blood Group Antigen Gene Mutation Database at NCBI, NIH

Transfusion medicine

General concepts	Apheresis (plasmapheresis, plateletpheresis, leukapheresis) Blood transfusion Coombs test (direct and indirect) Cross-matching Exchange transfusion International Society of Blood Transfusion Intraoperative blood salvage ISBT 128 Transfusion reactions

Blood group systems / blood types	ABO Chido-Rodgers Colton Cromer Diego Dombrock Duffy Er FORS Gerbich GIL GLOB Hh Ii Indian JR JMH Kell (Xk) Kidd Knops Lan Lewis Lutheran LW MNS OK P Raph Rh and RHAG Scianna T-Tn Vel Xg Yt Other

Blood products / blood donation	Whole blood Platelets Red blood cells Plasma / Fresh frozen plasma / PF24 (Cryoprecipitate + Cryosupernatant) Blood substitutes

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