ZRSR1

Zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
Identifiers
Symbols	ZRSR1 ; U2AF1-RS1; U2AF1L1; U2AF1P; U2AF1RS1; U2AFBPL; ZC3H21
External IDs	OMIM: 601079 MGI: 98885 GeneCards: ZRSR1 Gene
Gene ontology Molecular function • nucleotide binding • RNA binding • metal ion binding Cellular component • nucleus • ribonucleoprotein complex Biological process • biological_process Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	7310	22183
Ensembl	ENSG00000212643	ENSMUSG00000044068
UniProt	Q15695	Q64707
RefSeq (mRNA)	n/a	NM_011663
RefSeq (protein)	n/a	NP_035793
Location (UCSC)	Chr 5: 112.23 – 112.23 Mb	Chr 11: 22.87 – 22.88 Mb
PubMed search

U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1 is a protein that in humans is encoded by the ZRSR1 gene.^[1][2]

References

1. Kalcheva I, Plass C, Sait S, Eddy R, Shows T, Watkins-Chow D, Camper S, Shibata H, Ueda T, Takagi N (Dec 1994). "Comparative mapping of the imprinted U2afbpL gene on mouse chromosome 11 and human chromosome 5". Cytogenet Cell Genet 68 (1–2): 19–24. doi:10.1159/000133881. PMID 7956352.
2. "Entrez Gene: ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1".

Further reading

• Kitagawa K, Wang X, Hatada I, Yamaoka T, Nojima H, Inazawa J, Abe T, Mitsuya K, Oshimura M, Murata A (1996). "Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1". Genomics 30 (2): 257–63. doi:10.1006/geno.1995.9879. PMID 8586425.
• Pearsall RS, Shibata H, Brozowska A, Yoshino K, Okuda K, deJong PJ, Plass C, Chapman VM, Hayashizaki Y, Held WA (1996). "Absence of imprinting in U2AFBPL, a human homologue of the imprinted mouse gene U2afbp-rs". Biochem. Biophys. Res. Commun. 222 (1): 171–7. doi:10.1006/bbrc.1996.0716. PMID 8630064.
• Tronchère H, Wang J, Fu XD (1997). "A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA". Nature 388 (6640): 397–400. doi:10.1038/41137. PMID 9237760.
• Ueno K, Kumagai T, Kijima T, Kishimoto T, Hosoe S (1998). "Cloning and tissue expression of cDNAs from chromosome 5q21-22 which is frequently deleted in advanced lung cancer". Hum. Genet. 102 (1): 63–8. doi:10.1007/s004390050655. PMID 9490301.
• Gama-Carvalho M, Carvalho MP, Kehlenbach A, Valcarcel J, Carmo-Fonseca M (2001). "Nucleocytoplasmic shuttling of heterodimeric splicing factor U2AF". J. Biol. Chem. 276 (16): 13104–12. doi:10.1074/jbc.M008759200. PMID 11118443.
• Förch P, Merendino L, Martínez C, Valcárcel J (2003). "U2 small nuclear ribonucleoprotein particle (snRNP) auxiliary factor of 65 kDa, U2AF65, can promote U1 snRNP recruitment to 5' splice sites". Biochem. J. 372 (Pt 1): 235–40. doi:10.1042/BJ20021202. PMC 1223361. PMID 12558503.