| Date | Event |
| January 1 |
Affiliation swaps in Florida: In Miami, 3 channels change their network affiliation: WTVJ moves to NBC from CBS, WCIX (now WFOR-TV) moves to CBS from Fox, and WSVN moves to Fox from NBC. In West Palm Beach, WPEC-TV switches from ABC to CBS, WTVX leaves CBS to become an independent, and ABC station WPBF signs on this day. |
| January 9 |
Pat Sajak quits the daytime version of the series Wheel of Fortune for a CBS late night talk show while remaining host of the nighttime version. His daytime hosting role will be assumed by Rolf Benirschke, then by Bob Goen when Wheel switches networks from NBC to CBS the next July. |
| February 20 |
Falcon Crest actress Jane Wyman is rushed to the hospital, after suffering from diabetes and a liver ailment. |
| Charlie O'Donnell returned to Wheel of Fortune as the announcer, following a nine-year absence. |
| March 2 |
Pepsi's controversial advertisement with Madonna and her song "Like a Prayer" aired during NBC's showing of The Cosby Show The same ad was run on ITV in the UK, 12 minutes into The Bill. |
| March 24 |
For the first time since 1973, NBC reruns the 1960 telecast of Peter Pan, with Mary Martin in the title role. Earlier that day, Sale of the Century and Super Password aired their final episodes. |
| April 8 |
Mike Myers joins the cast of the series Saturday Night Live. |
| April 30 |
CNBC, NBC's answer to the Financial News Network, launched (CNBC and FNN would merge two years later). |
| May 11 |
In the series finale of Dynasty, Blake Carrington, Alexis Colby, Dex Dexter and Fallon Carrington Colby are stuck in mortal peril. |
| May 18 |
Donna Mills makes her final regular appearance as villainess Abby on Knots Landing. |
| August 14 |
Cliff and Nina Warner marry one another for the fourth (and seemingly final) time on All My Children, a record that has not been matched for soap operas. |
| September 4 |
The Family Channel debuts its children programming block Fun Town. |
| September 22 |
ABC debuts TGIF from 8:00pm to 10:00pm, a new programming block for Friday nights with four shows (Full House, Family Matters, Perfect Strangers, and Just the Ten of Us), it also includes interstitial hosts. This block would become a rating hit throughout the 1990s, lasting until 2000. |
| September 30 |
NBC broadcasts its final Major League Baseball Game of the Week (before the program is transferred to CBS). Bob Costas and Tony Kubek called the action from Toronto's SkyDome, as the Toronto Blue Jays defeated the Baltimore Orioles to clinch the American League Eastern Division title. |
| October 6 |
Jane Wyman is already on medical leave from Falcon Crest, when her character, Angela Channing, is in a coma. |
| October 17 |
Four minutes into ABC's broadcast of Game 3 of the World Series, the Lome Prieta earthquake occurred, forcing a ten-day delay of the series. |
| November 15 |
The Comedy Channel debuted (become Comedy Central two years later). |
| December 18 |
A seldom-seen 1956 Christmas special episode of I Love Lucy is re-broadcast by CBS. |