2'-hydroxydaidzein reductase

2'-hydroxydaidzein reductase
Identifiers
EC number 1.3.1.51
CAS number 126125-01-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a 2'-hydroxydaidzein reductase (EC 1.3.1.51) is an enzyme that catalyzes the chemical reaction

2'-hydroxy-2,3-dihydrodaidzein + NADP+ \rightleftharpoons 2'-hydroxydaidzein + NADPH + H+

Thus, the two substrates of this enzyme are 2'-hydroxy-2,3-dihydrodaidzein and NADP+, whereas its 3 products are 2'-hydroxydaidzein, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2'-hydroxy-2,3-dihydrodaidzein:NADP+ 2'-oxidoreductase. Other names in common use include NADPH:2'-hydroxydaidzein oxidoreductase, HDR, and 2'-hydroxydihydrodaidzein:NADP+ 2'-oxidoreductase. This enzyme participates in isoflavonoid biosynthesis.

References

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