2-Ketoarginine methyltransferase

2-Ketoarginine methyltransferase
Identifiers
EC number 2.1.1.243
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

2-Ketoarginine methyltransferase (EC 2.1.1.243, mrsA (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:5-carbamimidamido-2-oxopentanoate S-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + 5-guanidino-2-oxopentanoate \rightleftharpoons S-adenosyl-L-homocysteine + 5-guanidino-3-methyl-2-oxopentanoate

The enzyme is involved in production of the rare amino acid 3-methylarginine.

References

  1. Braun, S.D., Hofmann, J., Wensing, A., Ullrich, M.S., Weingart, H., Völksch, B. and Spiteller, D. (2010). "Identification of the biosynthetic gene cluster for 3-methylarginine, a toxin produced by Pseudomonas syringae' pv. syringae 22d/93". Appl. Environ. Microbiol. 76: 2500–2508. doi:10.1128/aem.00666-09. PMID 20190091.

External links

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