4-methyleneglutaminase

4-methyleneglutaminase
Identifiers
EC number	3.5.1.67
CAS number	86855-36-9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a 4-methyleneglutaminase (EC 3.5.1.67) is an enzyme that catalyzes the chemical reaction

4-methylene-L-glutamine + H₂O $\rightleftharpoons$ 4-methylene-L-glutamate + NH₃

Thus, the two substrates of this enzyme are 4-methylene-L-glutamine and H₂O, whereas its two products are 4-methylene-L-glutamate and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is 4-methylene-L-glutamine amidohydrolase. Other names in common use include 4-methyleneglutamine deamidase, and 4-methyleneglutamine amidohydrolase. This enzyme participates in c5-branched dibasic acid metabolism.

References

• Ibrahim SA, Lea PJ and Fowden L (1984). "Preparation and properties of 4-methyleneglutaminase from the leaves of peanut (Arachis hypogaea)". Phytochemistry 23 (8): 1545–1549. doi:10.1016/S0031-9422(00)83436-6.