Ammonia monooxygenase

Ammonia monooxygenase
Identifiers
EC number	1.14.99.39
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Ammonia monooxygenase (EC 1.14.99.39, AMO) is an enzyme,^{[1][2][3][4][5][6][7][8][9]} which catalyses the following chemical reaction

ammonia + AH₂ + O₂ $\rightleftharpoons$ NH₂OH + A + H₂O

Ammonia monooxygenase contains copper and possibly nonheme iron.

References

1. Hyman, M.R., Page, C.L. and Arp, D.J. (1994). "Oxidation of methyl fluoride and dimethyl ether by ammonia monooxygenase in Nitrosomonas europaea". Appl. Environ. Microbiol. 60 (8): 3033–3035. PMC 201762. PMID 8085841.
2. Bergmann, D.J. and Hooper, A.B. (1994). "Sequence of the gene, amoB, for the 43-kDa polypeptide of ammonia monoxygenase of Nitrosomonas europaea". Biochem. Biophys. Res. Commun. 204 (2): 759–762. doi:10.1006/bbrc.1994.2524. PMID 7980540.
3. Holmes, A.J., Costello, A., Lidstrom, M.E. and Murrell, J.C. (1995). "Evidence that particulate methane monooxygenase and ammonia monooxygenase may be evolutionarily related". FEMS Microbiol. Lett. 132: 203–208. doi:10.1111/j.1574-6968.1995.tb07834.x. PMID 7590173.
4. Zahn, J.A., Arciero, D.M., Hooper, A.B. and DiSpirito, A.A. (1996). "Evidence for an iron center in the ammonia monooxygenase from Nitrosomonas europaea". FEBS Lett. 397 (1): 35–38. doi:10.1016/s0014-5793(96)01116-7. PMID 8941709.
5. Moir, J.W., Crossman, L.C., Spiro, S. and Richardson, D.J. (1996). "The purification of ammonia monooxygenase from Paracoccus denitrificans". FEBS Lett. 387 (1): 71–74. doi:10.1016/0014-5793(96)00463-2. PMID 8654570.
6. Whittaker, M., Bergmann, D., Arciero, D. and Hooper, A.B. (2000). "Electron transfer during the oxidation of ammonia by the chemolithotrophic bacterium Nitrosomonas europaea". Biochim. Biophys. Acta 1459 (2-3): 346–355. doi:10.1016/s0005-2728(00)00171-7. PMID 11004450.
7. Arp, D.J., Sayavedra-Soto, L.A. and Hommes, N.G. (2002). "Molecular biology and biochemistry of ammonia oxidation by Nitrosomonas europaea". Arch. Microbiol. 178: 250–255. doi:10.1007/s00203-002-0452-0. PMID 12209257.
8. Gilch, S., Meyer, O. and Schmidt, I. (2009). "A soluble form of ammonia monooxygenase in Nitrosomonas europaea". Biol. Chem. 390 (9): 863–873. doi:10.1515/BC.2009.085. PMID 19453274.
9. Rasche, M.E., Hicks, R.E., Hyman, M.R. and Arp, D.J. (1990). "Oxidation of monohalogenated ethanes and n-chlorinated alkanes by whole cells of Nitrosomonas europaea". J. Bacteriol. 172 (9): 5368–5373. PMC 213201. PMID 2394686.

External links

• Ammonia monooxygenase at the US National Library of Medicine Medical Subject Headings (MeSH)