Angelicin synthase

Angelicin synthase
Identifiers
EC number 1.14.13.115
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Angelicin synthase (EC 1.14.13.115, CYP71AJ4 (gene)) is an enzyme with systematic name (+)-columbianetin,NADPH:oxygen oxidoreductase .[1] This enzyme catalyses the following chemical reaction

(+)-columbianetin + NADPH + H+ + O2 \rightleftharpoons angelicin + NADP+ + acetone + 2 H2O

Angelicin synthase is a P450 monooxygenase enzyme.

References

  1. Larbat, R., Hehn, A., Hans, J., Schneider, S., Jugde, H., Schneider, B., Matern, U. and Bourgaud, F. (2009). "Isolation and functional characterization of CYP71AJ4 encoding for the first P450 monooxygenase of angular furanocoumarin biosynthesis". J. Biol. Chem. 284 (8): 4776–4785. doi:10.1074/jbc.M807351200. PMID 19098286.

External links

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