Anthranilate N-methyltransferase

anthranilate N-methyltransferase
Identifiers
EC number	2.1.1.111
CAS number	123779-15-7
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, an anthranilate N-methyltransferase (EC 2.1.1.111) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + anthranilate $\rightleftharpoons$ S-adenosyl-L-homocysteine + N-methylanthranilate

Thus, the two substrates of this enzyme are S-adenosyl methionine and anthranilate, whereas its two products are S-adenosylhomocysteine and N-methylanthranilate.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:anthranilate N-methyltransferase. This enzyme is also called anthranilic acid N-methyltransferase. This enzyme participates in acridone alkaloid biosynthesis.

References

• Eilert U and Wolters B (1989). "Elicitor induction of S-adenosyl-L-methionine-anthranilic acid N-methyltransferase activity in cell-suspension and organ-cultures of Ruta graveolens L". Plant Cell, Tissue Organ Cult. 18: 1–18. doi:10.1007/BF00033461.