Asoxime chloride

Asoxime chloride

Systematic (IUPAC) name
4-carbamoyl-1-[({2-[(E)-(hydroxyimino)methyl]pyridinium-1-yl}methoxy)methyl]pyridinium dichloride
Clinical data
Legal status	Experimental
Routes of administration	Intramuscular injection
Identifiers
CAS Number	34433-31-3
ATC code	None
PubChem	CID 5484128
ChemSpider	13004322
ChEMBL	CHEMBL33051
Chemical data
Formula	C14H16Cl2N4O3
Molar mass	359.21 g/mol
SMILES C1=CC=[N+](C(=C1)/C=N/O)COC[N+]2=CC=C(C=C2)C(=O)N.[Cl-].[Cl-]
InChI InChI=1S/C14H14N4O3.2ClH/c15-14(19)12-4-7-17(8-5-12)10-21-11-18-6-2-1-3-13(18)9-16-20;;/h1-9H,10-11H2,(H-,15,19);2*1H Key:QELSIJXWEROXOE-UHFFFAOYSA-N
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Asoxime chloride, or more commonly HI-6, is a Hagedorn oxime used in the treatment of organophosphate poisoning.^[1]

References

1. Cochran, R.; Kalisiak, J.; Küçükkilinç, T.; Radic, Z.; Garcia, E.; Zhang, L.; Ho, K. -Y.; Amitai, G.; Kovarik, Z.; Fokin, V. V.; Sharpless, K. B.; Taylor, P. (2011). "Oxime-assisted Acetylcholinesterase Catalytic Scavengers of Organophosphates That Resist Aging". Journal of Biological Chemistry 286 (34): 29718–29724. doi:10.1074/jbc.M111.264739. PMC 3191013. PMID 21730071.