Autapse
An autapse is a chemical synapse from a neuron onto itself. It can also be described as a synapse formed by the axon of a neuron on its own dendrites, in vivo or in vitro.
Discovered in 1972,[1] they were originally thought to be a biological curiosity, but are now assumed to serve some purpose[2] (though their general function remains unknown), as they have been found to be common in some circuits of the visual cortex.[3]
References
- ↑ Van der Loos, H.; Glaser, E. M. (1972). "Autapses in neocortex cerebri: synapses between a pyramidal cell's axon and its own dendrites". Brain Research 48: 355–60. doi:10.1016/0006-8993(72)90189-8. PMID 4645210. (subscription required (help)).
- ↑ Bekkers, J. M. (1998). "Neurophysiology: Are autapses prodigal synapses?". Current Biology 8 (2): R52–R55. doi:10.1016/s0960-9822(98)70033-8. PMID 9427636. (subscription required (help)).
- ↑ Tamás, G.; Buhl, E. H.; Somogyi, P. (1997). "Massive autaptic self-innervation of GABAergic neurons in cat visual cortex". Journal of Neuroscience 17 (16): 6352–6364. PMID 9236244. (free full text)
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