Benzoyl-CoA 2,3-dioxygenase

Benzoyl-CoA 2,3-dioxygenase
Identifiers
EC number	1.14.12.21
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Benzoyl-CoA 2,3-dioxygenase (EC 1.14.12.21, benzoyl-CoA dioxygenase/reductase, BoxBA, BoxA/BoxB system) is an enzyme with systematic name benzoyl-CoA,NADPH:oxygen oxidoreductase (2,3-hydroxylating).^[1][2][3] This enzyme catalyses the following chemical reaction

benzoyl-CoA + NADPH + H⁺ + O₂ $\rightleftharpoons$ 2,3-dihydro-2,3-dihydroxybenzoyl-CoA + NADP⁺

Benzoyl-CoA 2,3-dioxygenase is involved in aerobic benzoate metabolism in Azoarcus evansii.

References

1. Zaar, A., Gescher, J., Eisenreich, W., Bacher, A. and Fuchs, G. (2004). "New enzymes involved in aerobic benzoate metabolism in Azoarcus evansii". Mol. Microbiol. 54 (1): 223–238. doi:10.1111/j.1365-2958.2004.04263.x. PMID 15458418.
2. Gescher, J., Zaar, A., Mohamed, M., Schagger, H. and Fuchs, G. (2002). "Genes coding for a new pathway of aerobic benzoate metabolism in Azoarcus evansii". J. Bacteriol. 184 (22): 6301–6315. doi:10.1128/jb.184.22.6301-6315.2002. PMC 151953. PMID 12399500.
3. Mohamed, M.E., Zaar, A., Ebenau-Jehle, C. and Fuchs, G. (2001). "Reinvestigation of a new type of aerobic benzoate metabolism in the proteobacterium Azoarcus evansii". J. Bacteriol. 183 (6): 1899–1908. doi:10.1128/JB.183.6.1899-1908.2001. PMC 95084. PMID 11222587.

External links

• Benzoyl-CoA 2,3-dioxygenase at the US National Library of Medicine Medical Subject Headings (MeSH)