Bundibugyo ebolavirus
| Species Bundibugyo ebolavirus | |
|---|---|
| Virus classification | |
| Group: | Group V ((-)ssRNA) |
| Order: | Mononegavirales |
| Family: | Filoviridae |
| Genus: | Ebolavirus |
| Species: | Bundibugyo ebolavirus |
| Member virus (Abbreviation) | |
|
Bundibugyo virus (BDBV) | |
The species Bundibugyo ebolavirus is the taxonomic home of one virus, Bundibugyo virus (BDBV), that forms filamentous virions and is closely related to the infamous Ebola virus (EBOV). The virus causes severe disease in humans in the form of viral hemorrhagic fever and is a Select Agent,[1] World Health Organization Risk Group 4 Pathogen (requiring Biosafety Level 4-equivalent containment),[2] National Institutes of Health/National Institute of Allergy and Infectious Diseases Category A Priority Pathogen,[3] Centers for Disease Control and Prevention Category A Bioterrorism Agent,[4] and is listed as a Biological Agent for Export Control by the Australia Group.[5]
Use of term
The species Bundibugyo ebolavirus is a virological taxon (i.e. a man-made concept) that was suggested in 2008 to be included in the genus Ebolavirus, family Filoviridae, order Mononegavirales.[6] The species has a single virus member, Bundibugyo virus (BDBV).[7] The members of the species are called Bundibugyo ebolaviruses.[7] The name Bundibugyo ebolavirus is derived from Bundibugyo (the name of the chief town of the Ugandan Bundibugyo District, where Bundibugyo virus was first discovered) and the taxonomic suffix ebolavirus (which denotes an ebolavirus species).[7]
Note
Bundibugyo ebolavirus is pronounced ˌbʊndiː’bʊdʒɔː iːˌboʊlə’vɑɪrəs (IPA) or boon-dee-boo-jaw ee-boh-luh-vahy-ruhs or boon-dee-boo-joh ee-boh-luh-vahy-ruhs in English phonetic notation.[7] According to the rules for taxon naming established by the International Committee on Taxonomy of Viruses (ICTV), the name Bundibugyo ebolavirus is always to be capitalized, italicized, never abbreviated, and to be preceded by the word "species". The names of its members (Bundibugyo ebolaviruses) are to be capitalized, are not italicized, and used without articles.[7] A formal proposal to accept this species into virus taxonomy has been submitted in 2010 and was accepted by the ICTV in early 2012.
Species inclusion criteria
A virus of the genus Ebolavirus is a member of the species Bundibugyo ebolavirus if:[7]
- it is endemic in Uganda
- it has a genome with three gene overlaps (VP35/VP40, GP/VP30, VP24/L)
- it has a genomic sequence different from Ebola virus by ≥30%, but different from that of Bundibugyo virus by <30%
References
- ↑ US Animal and Plant Health Inspection Service (APHIS) and US Centers for Disease Control and Prevention (CDC). "National Select Agent Registry (NSAR)". Retrieved 2011-10-16.
- ↑ US Department of Health and Human Services. "Biosafety in Microbiological and Biomedical Laboratories (BMBL) 5th Edition". Retrieved 2011-10-16.
- ↑ US National Institutes of Health (NIH), US National Institute of Allergy and Infectious Diseases (NIAID). "Biodefense - NIAID Category A, B, and C Priority Pathogens". Retrieved 2011-10-16.
- ↑ US Centers for Disease Control and Prevention (CDC). "Bioterrorism Agents/Diseases". Retrieved 2011-10-16.
- ↑ The Australia Group. "List of Biological Agents for Export Control". Retrieved 2011-10-16.
- ↑ Towner, J. S.; Sealy, T. K.; Khristova, M. L.; Albarino, C. G.; Conlan, S.; Reeder, S. A.; Quan, P. L.; Lipkin, W. I.; et al. (2008). "Newly discovered Ebola virus associated with hemorrhagic fever outbreak in Uganda". PLoS Pathogens 4 (11): e1000212. doi:10.1371/journal.ppat.1000212. PMC 2581435. PMID 19023410.
- 1 2 3 4 5 6 Kuhn, Jens H.; Becker, Stephan; Ebihara, Hideki; Geisbert, Thomas W.; Johnson, Karl M.; Kawaoka, Yoshihiro; Lipkin, W. Ian; Negredo, Ana I; et al. (2010). "Proposal for a revised taxonomy of the family Filoviridae: Classification, names of taxa and viruses, and virus abbreviations". Archives of Virology 155 (12): 2083–103. doi:10.1007/s00705-010-0814-x. PMC 3074192. PMID 21046175.
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