Butyrate—CoA ligase

butyrate-CoA ligase
Identifiers
EC number 6.2.1.2
CAS number 9080-51-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a butyrate-CoA ligase, also known as XM-ligase, (EC 6.2.1.2) is an enzyme that catalyzes the chemical reaction

ATP + an acid + CoA \rightleftharpoons AMP + diphosphate + an acyl-CoA

The 3 substrates of this enzyme are ATP, acid, and CoA, whereas its 3 products are AMP, diphosphate, and acyl-CoA.

This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. This enzyme participates in butanoate metabolism.

Nomenclature

The systematic name of this enzyme class is butanoate:CoA ligase (AMP-forming). Other names in common use include:

References

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