C9orf86
| RAB, member RAS oncogene family-like 6 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | RABL6 ; C9orf86; PARF; RBEL1; pp8875 | ||||||||||||
| External IDs | OMIM: 610615 MGI: 2442633 HomoloGene: 11674 GeneCards: RABL6 Gene | ||||||||||||
| |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 55684 | 227624 | |||||||||||
| Ensembl | ENSG00000196642 | ENSMUSG00000015087 | |||||||||||
| UniProt | Q3YEC7 | Q5U3K5 | |||||||||||
| RefSeq (mRNA) | NM_001173988 | NM_001024616 | |||||||||||
| RefSeq (protein) | NP_001167459 | NP_001019787 | |||||||||||
| Location (UCSC) |
Chr 9: 136.81 – 136.96 Mb |
Chr 2: 25.58 – 25.61 Mb | |||||||||||
| PubMed search | |||||||||||||
Putative GTP-binding protein Parf is a protein that in humans is encoded by the C9orf86 gene.[1][2][3][4]
Interactions
C9orf86 has been shown to interact with MDFI.[5]
References
- ↑ Tompkins V, Hagen J, Zediak VP, Quelle DE (Mar 2006). "Identification of novel ARF binding proteins by two-hybrid screening". Cell Cycle 5 (6): 641–6. doi:10.4161/cc.5.6.2560. PMID 16582619.
- ↑ Montalbano J, Jin W, Sheikh MS, Huang Y (Dec 2007). "RBEL1 is a novel gene that encodes a nucleocytoplasmic Ras superfamily GTP-binding protein and is overexpressed in breast cancer". The Journal of Biological Chemistry 282 (52): 37640–9. doi:10.1074/jbc.M704760200. PMID 17962191.
- ↑ Montalbano J, Lui K, Sheikh MS, Huang Y (Jul 2009). "Identification and characterization of RBEL1 subfamily of GTPases in the Ras superfamily involved in cell growth regulation". The Journal of Biological Chemistry 284 (27): 18129–42. doi:10.1074/jbc.M109.009597. PMC 2709392. PMID 19433581.
- ↑ "Entrez Gene: C9orf86 chromosome 9 open reading frame 86".
- ↑ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Further reading
- Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Cui YP, Wang JB, Zhang XY, Bi MX, Guo LP, Lu SH (Sep 2003). "Using yeast two-hybrid system to identify ECRG2 associated proteins and their possible interactions with ECRG2 gene". World Journal of Gastroenterology 9 (9): 1892–6. PMID 12970870.
- Cui Y, Wang J, Zhang X, Lang R, Bi M, Guo L, Lu SH (Mar 2003). "ECRG2, a novel candidate of tumor suppressor gene in the esophageal carcinoma, interacts directly with metallothionein 2A and links to apoptosis". Biochemical and Biophysical Research Communications 302 (4): 904–15. doi:10.1016/S0006-291X(03)00122-0. PMID 12646258.
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